This is a lie, it's a total lie.

这是个谎言，个彻头彻尾的谎言。

The point I'm trying to make is that I am the most unpleasant, rude, ignorant, and all round obnoxious arsehole that anyone could possibly have misfortune to meet.

想说的是，是最讨厌、最粗鲁、最无知的人、彻头彻尾的讨厌鬼，任何人遇到都是种不幸。

" He accused me of being 'Dumbledore's man through and through.'"

“他指责‘彻头彻尾是邓布利多的人’”。

President Trump described it as an unmitigated disaster for his opponents.

特朗普总统认为这对他的对手而言是彻头彻尾的。

In that case, I'm a fool, a thorough fool.

那这样的话，确实是个傻子，个彻头彻尾的傻子。

To this day, I'm still Currier House through and through.

直到今天，是彻头彻尾的 Currier House。

To ignore adversity is to succumb to the ultimate self-delusion.

而忽视逆塊则无异于彻头彻尾的自欺骗。

Doing nothing and complaining is outright hypocrisy. You don't have to be a whisper.

什么事都不做而抱怨是彻头彻尾的伪善。你不必当个小声说话的人。

Is he a complete and utter dilettante?

他是个彻头彻尾的门外汉吗？

Half of marriages between evangelical Protestants and non-evangelicals fail, and prominent evangelical pastors warn of the “emotional anguish” of marriage to someone who does not share their strict interpretation of faith.

福音派新教徒和非福音教徒的婚姻半数都走向破裂，举足轻重的福音派牧师警告双方不去彻头彻尾地分享对方宗教教义，到头来尝到的只是这种婚姻产生的“痛苦情绪”。

We cannot hear Van Gogh and yet this work speaks for him and creates a universal and relatable pain that is downright palpable.

们听不到梵高的声音，但这项工作为他说话，并创造了种普遍且相关的痛苦 ，这种痛苦是彻头彻尾的可触知的。

Even with this constraint, his exhaustive investigations yielded some remarkably accurate conclusions.

即使在这样的限制下，他彻头彻尾地调查，还是得到了些非常正确的结论。

And they said the satellite's smartphone was still working, so at least that's not a total piece of space junk.

他们说卫星上的通话设备还能使用，至少它不是彻头彻尾的太空垃圾。

Oh yeah! The acting is the definition of cringe!

哦，是的！电影的表演就是彻头彻尾的" cringe" ！

Am I gonna be seen as a complete failure?

会被视为彻头彻尾的失败者吗？

And it was an unmitigated disaster — and that was where the light bulb moment for Mumsnet came.

这是场彻头彻尾的——这就是“妈妈网”这想法灵光现的时刻。

Some of these myths are just exaggerations of actual facts, while others are downright falsehoods.

有些神话只是对事实的夸大，而另些则是彻头彻尾的谎言。

They are the opposite of outright lies. These types of lies are direct.

它们都在彻头彻尾的谎言的对立面。这类型（outright lies）的谎言都是直接的。

According to Mr Zhu, they blurred the line between regulated traditional medicine and outright quackery.

朱表示，他们模糊了受监管的传统医药与彻头彻尾的江湖医术之间的界限。

And then, of course, this exaggeration becomes lying outer that lying, and we don't want to listen to people we know are lying to us.

当这种夸大后来就变成了说谎。彻头彻尾的说谎，们就不想听这种们知道会说谎的人。