When a synesthete comes down with a cold, flu or something like an ear infection, it can affect how they experience their condition, either strengthening or weakening it, or making them feel out of whack and not right.
Not only can your dog sense when you have a cold, but domestic dogs have shown an aptitude for detecting both much smaller mood fluctuations and far more serious physical conditions.
And Holmes is rarely enthralled to the English Legal System, he much prefers enacting his own form of natural justice to sticking to the letter of law.
Co-opting nature's viruses to deliver base editors instead of the molecules that give you a cold is one of several promising delivery strategies that's been successfully used.