We all have inside us what we might term a true working self, a set of inclinations and capacities that long to exert themselves on the raw material of reality.
It combines contagiousness and lethality in a ferocious mixture that Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases, has called his " worst nightmare."
Here, Professor Rosie Campbell, Director of the Global Institute for Women's Leadership, explains to BBC World Service programme, The Real Story, how Mrs Thatcher's solution to this problem was to appear more masculine.