As seen in other animals, the lack of myostatin can invoke unnatural amounts of muscle.

此亦见于其他动物中，素减少会导致肉量的不正常增长。

Rather than beefing up an athlete's muscles, another new class of drugs, myostatin inhibitors, slow the routine breakdown of muscle tissue, offering an alternative way of increasing strength.

另一类新药，“素制剂”，它无法增强运动员的肉，而是通过减缓肉组织的常规分解来增强力量。

Myostatin is a regulating protein that alters the rate of muscle growth, creating a genetic muscle ceiling.

素是一种调节蛋白，通过制造肉外壁改变肉增长率。

The more myostatin present, the lower the amount of muscle you can build.

素越多，肉量越多。

The protein follistatin, has an antagonist effect to myostatin, diminishing myostatin's muscle limiting effect.

卵泡素蛋白与素抗作用，它能降低素对肉的限制。

With roughly 150 milligrams of epicatechin supplementation per day, the 6 middle-aged subjects saw a 16.6% myostatin decrease and a 49.2% follistatin increase.

每日 150 毫克的表儿茶素补剂，使六位中年实验者的素降低 16.6%，卵泡素则增长了 49.2%。

Fittingly, if your goal is to build muscle, you want myostatin reduced, but not to the point of completely removing it.

若你的目标是健身增，你会希望减低素但又不想完全消除它。

One thing that one would do clinically would get a cystatin C to correct and get a corrected GFR to see if it's within the normal range.

临床上会做的一项检查是胱素C，以校正并获得一个修正后的肾小球滤过率（GFR），看看是否正常范围内。

Well, the other thing is, physicians listening to this, please make this another reason to just look at cystatin C, please.

还有，听这个节目的医生们，请再把这个当作一个理由，去关注一下胱素C。

Follistatin and myostatin modulators, but for adults, it's probably not going to be a really significant driving force.

卵泡素和肉生长制剂调节剂，但对于成年人来说， 可能不会成为非常显著的驱动力。

Cystatin C is a far more accurate way to measure and estimate GFR and you don't have this problem of getting the confounded creatine levels increased.

胱素C是一种更准确的测量和估算肾小球滤过率（GFR）的方法，你不会遇到酐水平被混淆而升高的问题。

But yeah, as far as like folistatin gene therapy, I think it's too early to recommend clinically.

不过，就目前而言，关于卵泡素基因疗法，我认为临床上推荐它还为时过早。

But my main question with Follistatin gene therapy is, you know, What is the main goal with this?

但我对卵泡素基因疗法的主要疑问是，你知道，它的主要目标是什么？

But going back to, you said before around the myostatin inhibitor, the bimagrumab, that one there, you say it was more effective than folistatin gene therapy.

回到之前提到的肉生长制剂，比格鲁单抗， 你说它比卵泡素基因疗法更有效。

Yeah, I've had patients get folistatin gene therapy.

是的，我有一些患者接受了卵泡素基因疗法。

If you look into what Follistatin does in structure with FSH, et cetera.

如果你深入研究卵泡素与促卵泡激素等结构上的作用。