The incidence of umbilicated indentation in astrocytoma, cerebral metastases and brain abscess was nearly the same, showing no value in qualitative diagnosis.
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The permeability of blood-brain barrier (BBB) was detected by Evans Blue (EB) leakage method, and the ultrastruncture of BBB, which contained astroglia, was observed under electron microscopy.
Well fibrosis is a process mediated by special cells called stellate cells, that sit between the sinusoid and hepatocyte, known as the perisinusoidal space.
And while astrocytomas can be graded I through IV, juvenile pilocytic astrocytomas are only grade I because they are generally benign and slow-growing.