Cyanopyridine,intermediate of rimifon, was synthesized from 4-picoline using vanadium oxide as a catalyst in a fixed-bed reactor, reached 99% conversion of 4-picoline, 88% selectivity and 87.

以4甲基吡啶为原料,在定床反应器含氧化钒的化剂发生气触氨氧化反应制备雷米封间体4氰基吡啶,4甲基吡啶的转化率为99%,4氰基吡啶的选择性为88%,收率为87。