METHOD Sphingomyelin was prepared through the process of separating erythrocyte from blood,erythrocytolysis,dehydration,dry,et al,and then hydrolyzed to ceramide by phospholipase C.
The part of quality of lysolecithin was studied and the results showed that lysolecithin had better quality of wetting ability and emulsion stability than phospholipid.
Methods By means of bicolour fluorescence and flow cytometry (FCM) analysis, the results were compared during different lay-out time, hemolysis time and washing time.
It was showed that APTT and CT in the presence of LALP were markedly prolonged,the formation of venous thrombosis was obviously preven ted without any hemolyzation.
It's venom possess neurotoxic, cardiotoxic and hemotoxic properties.The clinical features of cobra bite are various, depend on the species and the ratio of the venous component.
The results shown that to some degree, they showed a destructive effect on Ehrlich ascitogenous cells and Mouse ascitic breast carcionma cells directly,but very little photo-hemolytic action.
This disease is an unusualsevere type of hemolytic disease of newborn (erythroblastosis fetalis)characterized by pathognomonic edema of whole body and the placenta.All the cases were dead fetuses.
RESULTS Weights of thoracic gland and spleen in mice increased significantly,the level of erythrolysin in the serum and the function of mononuclear phagocyte in mice were enhanced.
METHODS The phagocytosis of macrophagus and weight coefficient of immune organs were determined and the effect of the drugs on the concentration changes of erythrolysin in the serum were detected.
First, they damage the RBC membrane, resulting in intramedullary hemolysis, or RBC breakdown in the bone marrow; or extravascular hemolysis, when RBCs are destroyed by macrophages in the spleen.
It becomes treacherous for red blood cells to navigate through, and before long, they slam up against a clot and get destroyed - a process called hemolysis.
Free hemoglobin in the plasma is bound by a molecule called haptoglobin and gets recycled, which is why a low haptoglobin level is a sign of intravascular hemolysis.
Fava beans, also known as broad beans, can cause some people to experience a sudden, rapid breakdown of their red blood cells — a condition known as hemolytic anemia.
Back in the 1950s, researchers found that some patients who received primaquine — an anti-malarial drug — developed hemolytic anemia and had lower levels of G6PD in their blood.
If she is not treated and becomes pregnant again with an Rh positive child, her child could develop Erythroblastosis Fetalis, also known as Hemolytic Disease of the Newborn.
With extravascular hemolysis, we have macrophages eating up red blood cells more than normal and unconjugated bilirubin production is ramped up, which is conjugated by the liver and sent to the gallbladder.
So there are even more of these threatening molecules in your body, and without their bodyguard enzyme to protect them, your red blood cells end up sustaining a lot of damage — and prompting hemolytic anemia.