Despite a high morphological similarity, tumors with allelic loss on the short arm of chromosome 1 (1pLOH) are more chemosensitive than those without 1pLOH.
尽管两种
在形态学上极其相似,但是1号染色体短臂上等位基因丢失

比没有丢失

敏感性要高得多。
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This process of adding more repeats is called repeat expansion and it happens way more in the production of sperm than of eggs, so both anticipation and new disease alleles generally happens when the father is the affected parent.
这种序列
复增加称为
复序列扩增,精子产生时发生异常的几率比卵子高,因此当父亲为受累
体时,会发生早现现象和新的疾病等位基因。