Despite a high morphological similarity, tumors with allelic loss on the short arm of chromosome 1 (1pLOH) are more chemosensitive than those without 1pLOH.
尽管

瘤在形态学上极其相似,但是1号染色体短臂上等位基
丢失的
瘤比没有丢失的药物敏感
要高得多。
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This process of adding more repeats is called repeat expansion and it happens way more in the production of sperm than of eggs, so both anticipation and new disease alleles generally happens when the father is the affected parent.
这种序列重复增加称为重复序列扩增,精子产生时发生异常
几率比卵子高,因此当父亲为受累个
时,会发生早现现象和新
疾病等
基因。