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Mannose is the proper excipient for the lyophilized paclitaxel nanoemulsions, and glyc...

冻干不仅解紫杉醇水溶性问题,而且解化学不稳定性。

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Newsweek

The breast, ovarian and lung cancer drug paclitaxel, the most well-known example, originally came from the Pacific yew tree.

举个最耳熟能详的例子,治疗乳腺癌、卵巢癌和肺癌的药物,最初萃取自太平树。

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Lex Fridman Podcast

I like this example actually that Lee gave me, which is to think about taxol.

我其实喜欢李给我的这个例子,就是思考一下

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Fast Facts Non-Small-Cell Lung Cancer

3 These were RCTs compared with docetaxel alone.

3 这些是与单用多西进行比较的随对照试验。

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Lex Fridman Podcast

There's no Taxol elsewhere in the universe.

宇宙其他地方没有

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Fast Facts Non-Small-Cell Lung Cancer

Docetaxel second-line chemotherapy can be improved upon by nintedanib or ramicurimab.

多西二线化疗可以通过尼达尼布或雷米库利单抗得

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Lex Fridman Podcast

And Taxol was not decided by the initial conditions.

并不是由初始条件决定的。

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Fast Facts Non-Small-Cell Lung Cancer

The study evaluated a neoadjuvant combination of nivolumab, carboplatin and paclitaxel for 3 cycles followed by surgery and adjuvant nivolumab for 1 year in 46 patients with resectable stage IIIA NSCLC.

该研究对 46 名可切除 IIIA 期 NSCLC 患者进行了纳武单抗、卡铂和新辅助组合治疗 3 个周期,随后进行手术和纳武单抗辅助治疗 1 年的评估。

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Lex Fridman Podcast

And we also put in a really complex molecule, Taxol.

我们还加入了一种非常复杂的分子,

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Lex Fridman Podcast

You know, Taxol is unique to earth.

要知道,是地球独有的。

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Fast Facts Non-Small-Cell Lung Cancer

The IMpower150 trial, comparing carboplatin, paclitaxel and bevacizumab (BCP) with or without atezolizumab (ABCP), included 124 EGFR positive patients.

IMpower150 试验比较了卡铂、和贝伐单抗 (BCP) 联合或不联合阿特珠单抗 (ABCP),纳入了 124 名 EGFR 阳性患者。

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Lex Fridman Podcast

So this is one of the reasons that Taxol fills 1.5 universes of space.

因此,这是占据1.5个宇宙空间的原因之一。

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