Symptoms of tuberous sclerosis are often related to the hamartomas in the brain which cause problems like seizures, learning difficulties, and cognitive deficits.
And there's one more problem: each individual nodule creates a temporal instability that raises the chances the portal might collapse as you go through it.
Individuals are also at an increased risk of developing a subependymal giant cell astrocytoma, or SEGA, which is a type of cancer that can arise from the subependymal nodules.
The sciatic nerve then passes beneath the piriformis muscle, and through the greater sciatic foramen, which is an opening formed by the pelvic bone, sacrospinous and sacrotuberous ligaments.
Lotus leaves repel water because they are covered with minuscule waxy nodules that stop water molecules bonding with a leaf's surface tissues, meaning those molecules bond with each other instead.
Here's a classic histology image of cirrhotic tissue, this clump of cells in the middle is the regenerative nodule, and these blue stains surrounding it are the bands of protein from the process of fibrosis.
The central wastelands beyond those moon-frosted cliffs were desert—barren rock, dunes, and blowing dust, an uncharted dry wilderness with here and there along its rim and perhaps scattered through it, knots of Fremen.