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Intein is an intervening polypeptide which can catalytic self-cleavage from a pre-protein accompanied by the concomitant joining of the two flanking polypeptides (the extein) through a peptide bond.

一个蛋体中的多序列,可以催化自身从蛋体中断裂,使两侧的蛋外显连接成成熟的蛋

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Even more strikingly, almost half of the peptides discovered were entirely new, without obvious sequence similarity to known antimicrobials, thus increasing the chances of circumventing existing resistance mechanisms.

更突出的是,发现的近一半是全新的,与知抗菌素没有明显的序列相似性,从而增加现有耐药机制的机会。

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3G, 401(K), a,
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