Some experts assert that this work signifies a paradigm shift in antibiotic discovery.

一些专家断言，这项工作标志着抗生素现范式转变。

This is the argument brought up to challenge this change of paradigm.

这是为挑战这种范式变化而提出点。

The ever-evolving illicit drug trade is shifting to a new paradigm.

不断演化非法毒品贸易正转变为一种新范式。

In this paradigm, as he explains, there were clear causalities, certainties.

正如他所解释，在这种范式中，有明确因果关系确定性。

The transition from one paradigm to another won't happen overnight.

从一种范式到另一种范式转变不会在一夜之间生。

The evidence makes clear it is time for a paradigm shift on testing.

证据清楚地表明，是时候转变测试范式了。

A research paradigm consists of three elements; ontology, epistemology, and methodology.

研究范式包括三个要素：本体、认方法。

The group that represents producers of television and movies said the agreement " represents a new paradigm."

代表电视电影制片人组织表示，这项协议“代表了一种新范式”。

This behavioral change is perhaps unsurprising when it's intentional, the result of domestication and a controlled breeding paradigm.

当这种行为变化是驯养控制繁殖范式结果时，它是有意，也许并不令人惊讶。

We need more resources, but very little change actually in practice came about. And then there was a paradigm.

更多资源 但是实际上生变化很少 然后出现了一种范式。

But, in management-speak, there's been a paradigm shift.

但是，在管理方面，已经生了范式转变。

This may be the point where we get that paradigm to change a little bit.

这可能是我们让范式稍微改变地方。

This is the beginning of a new paradigm in medicine.

这是医学新范式开始。

There is multitrillion dollars to be made from paradigm shifts.

从范式转变中可赚取数万亿美元。

And much like the case we just did, here's kind of very basic paradigm.

就像我们刚才做案例一，这是一个非常基本范式。

You must take conscious control over the paradigm, remove and replace it.

你必须有意地控制这个范式， 移除并替换它。

So please think of these as signposts, approaches, paradigms that give some science for satisfaction.

所以请把这些视为路标、方法、范式，它们能为满足感提供一些科学依据。

So, what can each of the three sociological paradigms tell us about sexuality?

么，每个社会学范式能告诉我们关于性一些什么信息呢？

The success of the Sony TR-55 caused a paradigm shift in the West.

索尼TR-55成功引起了西方一场范式转移。

The Apollo guidance computer was the first computer to use them----a huge paradigm shift.

阿波罗导航计算机是第一台使用它们计算机——这是一个巨大范式转移。