All the C3 allotype was C3S.The gene frequency was 1.
且所有
第三补体异型均
C3S,
基因频率
1。
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When the abnormal IgA1-IgG immune complexes deposit in the mesangium, the alternative complement pathway is activated, leading to the release of proinflammatory cytokines and migration of macrophages into the kidney, all of which contributes to glomerular injury.
当异常的IgA1-IgG免疫复
沉积
系膜上时,补体旁路途径被激活,导致
炎因子的释放,同时
进巨噬细胞向肾迁移,以上所有反应会导致肾小球的损伤。