The conjugates of the present invention also exhibit an extended half-life in vivo compared to the corresponding unconjugated cytokine.
相对

合的细胞因
、趋化因
、生长因
和多肽激素,本发明的
合物也

和
外显示出延长的半衰期。
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The immune system responds to the antigen by flooding the subarachnoid space with white blood cells, which, release chemokines - and create inflammation and this results in the classic triad of symptoms: headaches, fevers, and neck stiffness.
免疫系统检测
病原体之
,向蛛网膜下腔注入白细胞,以释放趋化因子,造成
;这会导致经典的脑膜

:头痛、发烧和颈部僵硬。