Aldosterone is part of a hormone family or axis which work together and are called the renin-angiotensin-aldosterone system.

酮属一特定激素家族或激素轴的一部，这些激素共同作用，被称为肾素-血管紧张素-酮系统。

Less aldosterone floating around in the blood causes the body to start dumping sodium from the blood into the urine.

血中酮减少使得尿钠排出增多。

The diagnosis of hyperaldosteronism is mainly done by measuring levels of renin and aldosterone.

酮增多症的诊断主要通过测定肾素与酮的水平来完成。

Secondary causes of hyperaldosteronism are usually due to excess aldosterone production in response to high levels of renin.

酮增多症的继发性原因通常由高水平肾素导致酮生成过多。

Now, an important hormone that helps regulate potassium reabsorption or secretion in the kidneys is aldosterone.

所以，肾脏中有一种重要的激素可以帮助调节钾的重吸收和，这就酮。

When there is less sodium, the body increases activity in the renin-angiotensin-aldosterone system or the RAAS.

当体内钠含量较少时，人体 RAA 系统（肾素血管紧张素酮系统）开始活跃。

Aldosterone has it's purpose, but it's not a hormone you want to regularly have high levels of.

酮有其作用，但在人体中，这种荷尔蒙的水平不能太高。

High aldosterone is associated with increased inflammation, Chronic kidney disease, Osteoporosis, and cardiovascular disease.

高酮水平会增加体内炎症，导致慢性肾病、骨质疏松症以及心血管疾病。

An important hormone that helps regulate potassium reabsorption or secretion in the kidneys is aldosterone.

肾脏中一种帮助调节钾重吸收或的重要激素叫酮。

Another example is a tumor that produces excess aldosterone, which just like renin, leads to fluid retention.

另一个例子肿瘤的生长也会产生过多的酮，一种类似肾素的物质，会导致液体的积存。

In particular, it's implicated in oxidative stress and myocardial fibrosis — an abnormal thickening of the heart valves.

酮与氧化应激和心肌纤维化（心脏瓣膜异常增厚）尤其相关。

This taking up more space issue triggers another mechanism in our body that causes the hormone aldosterone to stop being released.

血管容量的增加触发另一机制造成酮这一激素停止释放。

Hyperaldosteronism can also be due to secondary causes where the pathology lies outside of the adrenal gland.

酮增多症也可以继发性的，即病变位肾上腺以外。

Other pathological conditions that cause increased aldosterone levels include compensated heart failure and cirrhosis.

其他导致酮水平增加的病理状况包括代偿期心衰和肝硬化。

Hyperaldosteronism can happen due to primary causes which is where the adrenal gland itself is responsible for the excess production of aldosterone.

酮增多症可以原发性的，即肾上腺本身产生了过量的酮。

This stimulates the release of aldosterone, which tries to bring blood pressure back up by telling the kidneys to retain more sodium and water.

这会刺激酮的释放，酮让肾脏保留更多的钠和水来尽量维持血压。

So in this case aldosterone levels are high and renin levels are low in.

因此，在这种情况下，酮水平较高，肾素水平较低。

As this study shows, a low salt diet increases aldosterone by more than 3 fold in healthy people.

这项研究显示，健康正常人采用低盐饮食，其体内酮水平将增加 3 倍有余。

This suggests that people actually following the WHO guidelines are chronically raising their aldosterone.

也就说，遵循世卫组织关盐摄入量建议的人们，他们体内的酮长期处较高水平。

With these medications around, aldosterone can't exert its effects.

有了这些药物，酮就无法发挥其作用了。