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Objective To evaluate the clinical and biochemical features of patients with aldosteronoma in adrenal incidentaloma.

分析肾上腺意外瘤中固酮瘤患者临床及征。

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Osmosis-内

Aldosterone is part of a hormone family or axis which work together and are called the renin-angiotensin-aldosterone system.

一特定激素家族或激素轴的一部激素共同作用,被称为肾素-血管紧张素-系统。

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Osmosis-内

Less aldosterone floating around in the blood causes the body to start dumping sodium from the blood into the urine.

血中减少使得尿钠排出增多。

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Osmosis-内

The diagnosis of hyperaldosteronism is mainly done by measuring levels of renin and aldosterone.

增多症的诊断主要通过测定肾素与的水平来完成。

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Osmosis-内

Secondary causes of hyperaldosteronism are usually due to excess aldosterone production in response to high levels of renin.

增多症的继发性原因通常是由高水平肾素导致生成过多。

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Osmosis-泌尿

Now, an important hormone that helps regulate potassium reabsorption or secretion in the kidneys is aldosterone.

所以,肾脏中有一种重要的激素可以帮助调节钾的重吸收和泌,就是

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WIL生活启示录

When there is less sodium, the body increases activity in the renin-angiotensin-aldosterone system or the RAAS.

当体内钠含量较少时,人体 RAA 系统(肾素血管紧张素系统)开始活跃。

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WIL生活启示录

Aldosterone has it's purpose, but it's not a hormone you want to regularly have high levels of.

有其作用,但在人体中,种荷尔蒙的水平不能太高。

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WIL生活启示录

High aldosterone is associated with increased inflammation, Chronic kidney disease, Osteoporosis, and cardiovascular disease.

水平会增加体内炎症,导致慢性肾病、骨质疏松症以及心血管疾病。

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Osmosis-泌尿

An important hormone that helps regulate potassium reabsorption or secretion in the kidneys is aldosterone.

肾脏中一种帮助调节钾重吸收或泌的重要激素叫

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Osmosis-心血管

Another example is a tumor that produces excess aldosterone, which just like renin, leads to fluid retention.

另一个例子是肿瘤的生长也会产生过多的,一种类似肾素的物质,会导致液体的积存。

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WIL生活启示录

In particular, it's implicated in oxidative stress and myocardial fibrosis — an abnormal thickening of the heart valves.

与氧化应激和心肌纤维化(心脏瓣膜异常增厚)尤其相关。

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Osmosis-内

This taking up more space issue triggers another mechanism in our body that causes the hormone aldosterone to stop being released.

血管容量的增加触发另一机制造成一激素停止释放。

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Osmosis-内

Hyperaldosteronism can also be due to secondary causes where the pathology lies outside of the adrenal gland.

增多症也可以是继发性的,即病变位肾上腺以外。

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Osmosis-内

Hyperaldosteronism can happen due to primary causes which is where the adrenal gland itself is responsible for the excess production of aldosterone.

增多症可以是原发性的,即肾上腺本身产生了过量的

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Osmosis-泌尿

Other pathological conditions that cause increased aldosterone levels include compensated heart failure and cirrhosis.

其他导致水平增加的病理状况包括代偿期心衰和肝硬化。

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Osmosis-消化

This stimulates the release of aldosterone, which tries to bring blood pressure back up by telling the kidneys to retain more sodium and water.

会刺激的释放,让肾脏保留更多的钠和水来尽量维持血压。

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Osmosis-内

So in this case aldosterone levels are high and renin levels are low in.

因此,在种情况下,水平较高,肾素水平较低。

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WIL生活启示录

As this study shows, a low salt diet increases aldosterone by more than 3 fold in healthy people.

项研究显示,健康正常人采用低盐饮食,其体内水平将增加 3 倍有余。

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WIL生活启示录

This suggests that people actually following the WHO guidelines are chronically raising their aldosterone.

也就是说,遵循世卫组织关盐摄入量建议的人们,他们体内的长期处较高水平。

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Osmosis-内

With these medications around, aldosterone can't exert its effects.

有了药物,就无法发挥其作用了。

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