Still in his mid-50s, he suffered severe osteoarthritis.

50多岁的时候， 他就备受骨节炎的折磨。

Even the most common type, osteoarthritis, is trickier to prevent than one might think.

即使要避免最常见的骨节炎，也比人们想象的难得多。

In arthritis, the patients usually have energy loss since fewer energy-carrying molecules are generated.

如果患有骨节炎，由的载能分子较少，患者通常会产能量损失。

Which can boost the risk of osteoarthritis and the need for hip replacement in middle age.

这会增加骨节炎的发病率从而使得患病者在中年时需要进行髋节置换手术。

Nowadays, it's thought that inflammation does indeed play an important role in the development of osteoarthritis.

现如今，炎症反应被认为确实在骨节炎病程发展中，起到了不忽视的作用。

The origins of osteoarthritis can often be traced to a patient's early life, from any seemingly ordinary joint injury.

骨节炎的病根，通常到患者早些年看似普通的节损伤。

Osteoarthritis is really common, and nearly everyone knows someone that suffers from it.

骨节炎十分常见，几乎每个人身边都有该病患者。

With Osteoarthritis, we're really talking about one particular kind of joint which is a synovial joint.

骨节炎中，我们讨论的是一种特殊的节——滑膜节。

Dolly who had to be put down in 2003 had aged prematurely because she developed osteoarthritis at a relatively young age.

多利在相对年轻的岁数患上骨节炎，因此未老先衰，2003年不得不被实施安乐死。

People can also develop things called osteoarthritis, where you actually lose cartilage and you have more kind of bone on bone.

人们也以患上叫做骨节炎的病，你实际上失去了软骨，你的骨头上有更多种类的骨头。

Finally, management and treatment of osteoarthritis can involve non-pharmacological approaches, like losing weight or moderate exercise, as well as physical therapy.

最后，骨节炎的治疗和处理常使用非药物疗法，如减肥或适当运动，以及物理疗法。

The researchers looked for signs of diabetes, high blood pressure, and osteoarthritis.

研究人员寻找糖尿病、高血压和骨节炎的迹象。

And they actually randomized these women who had knee osteoarthritis into one of two groups.

戴维斯：他们实际上将这些患有膝骨节炎的女性随机分成了两组。

We have, for example, an epidemic of osteoarthritis today.

例如，我们现在有一种骨节炎的流行病。

And his knees have the early signs of osteoarthritis.

他的膝盖出现了早期骨节炎的迹象。

This leads to the flood of enzymes and degradation seen in osteoarthritis, but is driven by different inflammatory proteins called cytokines.

也出现骨节炎中产大量酶和削弱节的现象，但由不同的炎症蛋白引起，这种蛋白称为细胞因子。

And I think, you know, we often used to think about osteoarthritis as a wear and tear problem.

而且我认为，我们过去常常把骨节炎看作是磨损导致的问题。

The origins of osteoarthritis can often be traced to a patient’s early life, from any seemingly ordinary joint injury.

骨节炎的起源通常以到患者的早年活，源任何看似普通的节损伤。

If Dolly was a typical example, it was possible that clones would die early of age-related diseases, like osteoarthritis.

如果多莉是一个典型的例子，克隆人有能会早死与年龄有的疾病， 比如骨节炎。

It's probably more effective than most traditional treatments for osteoarthritis.

它能比大多数传统治疗骨节炎的方法更有效。