Still in his mid-50s, he suffered severe osteoarthritis.

50多岁时候， 他就备受骨关节炎折磨。

Dolly who had to be put down in 2003 had aged prematurely because she developed osteoarthritis at a relatively young age.

多利在相对年轻岁数患上骨关节炎，因此未老先衰，2003年不得不被实施安乐死。

While being hospitalized overnight due to mysterious flu-like symptoms, he missed a Harry Potter convention at Universal Studios, which fueled tabloid speculation regarding his reported alcohol problems.Coltrane's health issues sadly worsened with his ongoing battles with diabetes and osteoarthritis.

因疑似流感样症状在医院过夜，他错过了在环球影城举行哈利·波特大会，这引发了小报对他酗酒问测。不幸是，随着他与糖尿病和骨关节炎持续斗争，科尔特兰健康问持续恶化。

Rather than doing that, instead it's more about, you know, why are we, why are we working to retire when we're in our 60s and we've got osteoarthritis in both our knees?

与其这样做，不如更多地去思考，你知道，为什么我，为什么我在 60 多岁时候工作退休，那时我两个膝盖都有骨关节炎？

Scientists have observed that bromelain has a host of other potential uses too, including as a treatment for osteoarthritis, autoimmune diseases, viral infections, burns, and breast cancer.

科学家观察到，菠萝蛋白酶也有许多其他潜在用途，包括作为骨关节炎、自身免疫性疾病、病毒感、和乳腺癌治疗方法。

We've seen evidence of improved pain scores and pain-free range of motion, factors critical to athletes, as well as improved bone mineral density in osteoarthritic individuals.

我看到了胶原蛋白对疼痛评分和无痛活动范围改善，这些对运动员至关重要因素，以及对骨关节炎患者骨密度改善。

Due to its anti-inflammatory properties, ibuprofen is also used to control pain and inflammation in the joints, bones, and muscles, for example, in conditions like osteoarthritis and rheumatoid arthritis.

由于其抗炎特性，布洛芬也被用于控制关节、骨骼和肌肉疼痛和炎症，比如骨关节炎和类风湿性关节炎等疾病。

People with osteoarthritis often feel stiffness in the morning, which usually lasts less than 1 hour but comes back at the end of the day.

骨关节炎患者往往感到晨僵，晨僵时间往往不超过一小时，但在一天结束时又会发生。

The mice used in the study were suffering from arthritis, meaning cells in their cartilage had degenerated and could not be repaired by themselves.

在这项研究中，研究者以骨关节炎小鼠模型为例进行了探索，这些小鼠软骨细胞已经退变、老化，无法自行修复。

This leads to the flood of enzymes and degradation seen in osteoarthritis, but is driven by different inflammatory proteins called cytokines.

也出现骨关节炎中产生大量酶和削弱关节现象，但由不同炎症蛋白引起，这种蛋白称为细胞因子。

People can also develop things called osteoarthritis, where you actually lose cartilage and you have more kind of bone on bone.

人也可以患上叫做骨关节炎病，你实际上失去了软骨，你骨头上有更多种类骨头。

Which can boost the risk of osteoarthritis and the need for hip replacement in middle age.

这会增加骨关节炎发病率从而使得患病者在中年时需要进行髋关节置换手术。

In arthritis, the patients usually have energy loss since fewer energy-carrying molecules are generated.

如果患有骨关节炎，由于新生载能分子较少，患者通常会产生能量损失。

It was once thought that the " itis" part of osteoarthritis was a misnomer, and that inflammation didn't play a role in its development, and that it was mostly a degenerative disease resulting from simple " wear and tear" .

人曾一度认为骨关节炎中“炎”字用词不当，因为当时认为病程发展中炎症反应并没有起到作用，骨关节炎仅仅是由于单纯磨损导致一种退行性疾病。

The origins of osteoarthritis can often be traced to a patient's early life, from any seemingly ordinary joint injury.

骨关节炎病根，通常可追溯到患者早些年看似普通关节损。

Even the most common type, osteoarthritis, is trickier to prevent than one might think.

即使要避免最常见骨关节炎，也比人想象难得多。

The biggest risk factor for osteoarthritis seems to be age, and often the cartilage degrades over longer periods of time, which makes it really hard to pinpoint one single culprit.

骨关节炎最大危险因素似乎是年龄，软骨逐渐退行性变需要很长时间，这让我很难找出罪魁祸首。

Nowadays, it's thought that inflammation does indeed play an important role in the development of osteoarthritis.

现如今，炎症反应被认为确实在骨关节炎病程发展中，起到了不可忽视作用。

With Osteoarthritis, we're really talking about one particular kind of joint which is a synovial joint.

骨关节炎中，我讨论是一种特殊关节——滑膜关节。

Also, joint injury, which brings with it a lot of inflammation, seems to be a major risk factor for osteoarthritis, as well as mechanical stress and obesity.

同时关节损也会带来大量炎症反应，这也成为骨关节炎一个重要危险因素，此外还有机械压力和肥胖因素等。