For example, as pinealomas, medulloblastomas, and ependymomas enlarge - the mass of the tumor can compress nearby ventricles blocking the flow of cerebrospinal fluid which causes swelling, called hydrocephalus.

例如，随着松果体瘤、胞瘤与室管膜瘤增，巨瘤可以压迫一旁脑室，阻断脑脊液流动，从而引起组织胀，称为脑水。

Now, while medulloblastoma may be the most common malignant tumor, the most common primary pediatric tumor is a type of astrocytoma called a juvenile pilocytic astrocytoma.

尽管胞瘤可能是最常见恶性瘤，最常见童原发脑瘤是一种星形胞瘤，称为青少年毛胞型星形胞瘤。

Because of this, medulloblastomas are typically only classified as grade IV.

因为这一特征，胞瘤通常只被分为IV级。

Histologically, medulloblastomas often have a feature called Homer-Wright rosettes, which are dense tangles of neurons and neuroglial cells, surrounded by ring-like structures formed by tumors cells.

组织学方面，胞瘤常具有一种特征，Homer-Wright菊形团：即瘤胞核围绕着密集缠结在一起神经胞和神经胶质胞突起排列。

Medulloblastomas originate from embryonic stem cells and they tend to be extremely aggressive.

胞瘤来源于胚胎干胞，它们往往极具侵袭性。

Overall, the most common malignant tumor is a medulloblastoma, which typically forms in or around the cerebellum, adjacent to the fourth ventricle.

总体而言，最常见童恶性脑瘤是胞瘤；它们通常在第四脑室旁小脑内或周围形成。

These patients had a lot more non-T cell stuff, specifically myeloid cells, you know, the immune system's first responders, but they can also be really suppressive in cancer settings.

这些患者体内有更多非T胞成分，特别是系胞——免疫系统第一道防线，但在癌症环境中它们也可能具有很强抑制作用。

They started with the more common myeloid cells, monocytes, macrophages, neutrophils.

他们首先研究了较为常见系胞，包括单核胞、巨噬胞和中性粒胞。

But the TME gets dominated by immunosuppressive cell types, particularly myeloid cells and stromal cells.

但瘤微环境（TME）被免疫抑制性胞类型主导，尤其是系胞和基质胞。