For example, as pinealomas, medulloblastomas, and ependymomas enlarge - the mass of the tumor can compress nearby ventricles blocking the flow of cerebrospinal fluid which causes swelling, called hydrocephalus.

例如，随着瘤、髓母瘤与室管膜瘤的增大，巨大的肿瘤可以压迫一旁的脑室，阻断脑脊液的流动，从而引起组织肿胀，称为脑水肿。

Now, while medulloblastoma may be the most common malignant tumor, the most common primary pediatric tumor is a type of astrocytoma called a juvenile pilocytic astrocytoma.

尽管髓母瘤可能是最常见的恶性肿瘤，最常见的童原发脑肿瘤是一种星形瘤，称为青少年毛型星形瘤。

Because of this, medulloblastomas are typically only classified as grade IV.

因为这一特征，髓母瘤通常只被分为IV级。

Histologically, medulloblastomas often have a feature called Homer-Wright rosettes, which are dense tangles of neurons and neuroglial cells, surrounded by ring-like structures formed by tumors cells.

组织学方面，髓母瘤常具有一种特征，Homer-Wright菊形团：即肿瘤围绕着密集缠结在一起的神经和神经胶质突起排列。

Medulloblastomas originate from embryonic stem cells and they tend to be extremely aggressive.

髓母瘤来源于胚胎干，它们往往极具侵袭性。

Overall, the most common malignant tumor is a medulloblastoma, which typically forms in or around the cerebellum, adjacent to the fourth ventricle.

总而言，最常见的童恶性脑肿瘤是髓母瘤；它们通常在第四脑室旁的小脑内或周围形成。

These patients had a lot more non-T cell stuff, specifically myeloid cells, you know, the immune system's first responders, but they can also be really suppressive in cancer settings.

这些患者内有更多非T成分，特别是髓系——免疫系统的第一道防线，但在癌症环境中它们也可能具有很强的抑制作用。

They started with the more common myeloid cells, monocytes, macrophages, neutrophils.

他们首先研究了较为常见的髓系，包括单、巨噬和中性粒。

But the TME gets dominated by immunosuppressive cell types, particularly myeloid cells and stromal cells.

但肿瘤微环境（TME）被免疫抑制性类型主导，尤其是髓系和基质。