Its main rivals are CSC, with around 10% of the market, and TLS contact, with around 7%.

它主要对手是约占10%份额CSC和约占7%TLScontact。

So did this study look at the TLSs using that spatial mapping technique?

这项研究是否使用了空间定位技术来分析TLS？

Using the spatial data, they could actually track the maturation state or the functional quality of these TLSs.

利用空间数据，他们实际上能够追踪这些三级淋巴结成熟态或功能质量。

They provocatively suggest these might represent the very earliest stages of formation for something called tertiary lymphoid structures, or TLSs.

他们颇具争议地提出，这些结可能代表了一种称为三级淋巴结（TLSs）早期形成阶段。

Then they saw declining TLSs, and finally, late stage or exhausted TLSs, where the functional signals were very low.

随后，他们观察到TLSs数量减少，最终出现晚期或耗竭态TLSs，其功能信号极低。

This brings us to those tertiary lymphoid structures, TLSs.

这使我们来到了三级淋巴结，即TLSs。

And definite, well-structured TLSs marked by specific molecules like PNAid were found in 18 out of 30.

在30例中，有18例发现了明确且结良好三级淋巴结（TLSs），这些结由PNAid等特异性分子标记。

It can actually promote things like CXCL13 expression and maybe even help TLSs form.

它实际上可能促进CXCL13表达，甚至有助于三级淋巴结（TLSs）形成。

Then we'll dive into the B cells and these things called tertiary lymphoid structures, or TLSs, the sort of immune backup crew.

然后我们将深入探讨B细胞以及一种被称为三级淋巴结（TLSs）疫辅助机制。

Exhausted but ICB-ready T cells, lots of TLSs built with B cells making tumor-specific antibodies, and myeloid cells cleaning up via ADCC.

耗竭但适合疫检查点阻断治疗T细胞，大量由B细胞建三级淋巴结（TLSs）产生肿瘤特异性抗体，以及髓系细胞通过ADCC清除癌细胞。

It seems crazy that this could happen, until you find out that all the big named companies that are using TLS encryption aren't actually paying for it.

这看起来很疯狂，直到你发现所有使用传输层安全加密大公司实际上都没有为此付费。

Then the really important ones, activated TLSs, which are characterized by high levels of functional immune signaling molecules, like cytokines, LTB, and CXCL13, showing they're really coordinating the fight.

然后是真正重要那些，活化三级淋巴结（TLS），其特征是功能性疫信号分子（如细胞因子、LTB和CXCL13）水平较高，表明它们正在积极协调疫反应。

So the data stream is encrypted, using an encryption tool called Transport Layer Security, or TLS. Your machine and the other machine are both given a one-time key for decoding that encryption.

所以数据流是使用一种名为传输层安全（TLS）加密工具进行加密。你设备和其他设备都会获得一个一次性密钥来解密这个加密。

Who is writing just assembly by no one writes assembly by hand other than like maybe that one guy that's developing TLS 1.3 and hand rolling a cryptography algorithm to be the fastest possible algorithm.

究竟是谁还在单纯地编写汇编代码呢？除了那位可能正在开发TLS 1.3，并亲手打造加密算法以追求极致速度专家外，几乎没人会手动编写汇编代码了。

We'll look at the state of the malignant cancer cells themselves, then this idea of a physical barrier built by other cells, the fibroblasts and macrophages, and finally, how the body's own immune structures, these TLSs, get suppressed.

我们将探讨恶性癌细胞自身态，接着分析由其他细胞——成纤维细胞和巨噬细胞——建物理屏障，最后了解机体自身疫结——这些三级淋巴结（TLS）——是如何被抑制。