To protect the pancreas, the acinar cells manufacture inactive forms of the enzymes called proenzymes, or zymogens.

为了保护，泡细胞会产生这些的无活性形式，称为“原”。

As the acinar cells become impaired they produce fewer pancreatic digestive enzymes, which results in pancreatic insufficiency.

当泡细胞受损时，它们产生的消化减少，引起能不全。

Cholecystokinin stimulates acinar cells in the pancreas to secrete digestive enzymes that travel through the pancreatic ducts and into the duodenum.

胆囊收缩素也能激的泡细胞产生消化；消化导管排出，进入十二指肠。

Alcohol also contributes to pancreatitis in other ways, though, for example, stimulating acinar cells to release inflammatory cytokines which attracts a strong immune reaction.

酒精还可以通过其它方式导致炎，比如促进泡细胞释放炎性细胞因子，而引起强烈的免疫反应。

With alcohol abuse it goes like this: alcohol increases zymogen secretion from acinar cells while decreasing fluid and bicarbonate production from the ductal epithelial cells.

酒精滥用是这样引发急性炎的：酒精增加泡细胞分泌原，同时让管上皮细胞减少生成水和碳酸氢盐。

As part of the subsequent healing process pancreatic stellate cells lay down fibrotic tissue which causes narrowing, or stenosis of the ducts, as well as acinar cell atrophy.

作为后续修复愈合过程的一部分，星状细胞会产生纤维化组织，造成导管狭窄及泡细胞萎缩。

When the pancreatic acinar cells are damaged or the the pancreatic ducts are blocked, often because of alcohol abuse or gallstones, the inactive zymogens that the pancreas produces can be prematurely converted to active digestive enzymes.

通常由酒精滥用或胆结石导致的泡细胞受损或管阻塞时，产生的无活性原可被过早转化为活性消化。