The partisan agonists are not wrong about the significance of the moment.

两党内部反应激动的那部分人对这个时刻的重要性的理解并无不妥。

Other researchers are also running studies on GLP-1 agonists and addiction.

其他研究人员也对GLP-1促效药和成瘾进行研究。

In the central nervous system, nicotinic receptors are on pre-synaptic axon terminals of neurons, and when nicotine binds to them, it triggers the release of neurotransmitters like dopamine, acetylcholine, and glutamate, which is why it's considered an acetylcholine agonist.

中枢神经系统中，烟碱受体分布突触前神经元的轴突末端，当尼古丁与受体结合后，会触发多巴胺、碱、谷氨酸盐等神经递质的释放，因此尼古丁被认为是一种碱受体兴奋剂。

Other choices include prokinetic medications, which increase the tone of the lower esophageal sphincter, and the GABA agonist baclofen, which inhibits transient LES relaxations, especially after meals.

其他选择包括促胃肠动力药，这会增加食管下括约肌的张力，以及GABA激动剂巴氯芬，它能抑制一过性LES松弛，尤其是饭后。

So, that said, beta-2-adrenergic antagonists, also known as beta blockers, and alpha-adrenergic agonists, both cause a shift in potassium out of the cells and into the blood.

所以就是说，β2肾上腺素受体拮抗剂，又叫β受体阻滞剂，还有α受体激动剂，都会使钾离子出细胞而入血。

The study focused GLP-1 receptor agonists, including semaglutide, which is sold as Ozempic to treat diabetes and is now widely prescribed for weight loss.

该研究GLP-1受体激动剂，包括用治疗糖尿病的Ozempic（司美格鲁肽），该药物现被广泛用减肥。

For example, the muscles that are mainly responsible for producing a certain movement are called that motion's prime movers, or agonist muscles.

例如，主要负责产生某种运动的肌肉被称为该运动的原动机，或激动肌。

Individuals with more severe forms of asthma might need additional treatments like daily corticosteroids, long-acting beta-adrenoceptor agonists, or leukotriene antagonists.

哮喘较为严重的患者可能需要额外的治疗，如日服皮质类固醇，施用长效的β肾上腺素受体激动剂或白三烯拮抗剂。

The drugs that are getting a lot of attention are a class of medications called GLP-1 agonists.

目前备受关注的药物是一类被称为GLP-1受体激动剂的药物。

Such a study cannot prove that GLP-1 agonists do not increase the risk of suicidal ideation.

这样的研究不能证明GLP-1激动剂不会增加自杀念头的风险。

" But no one had comprehensively investigated the effectiveness and risks of GLP-1 receptor agonists across all possible health outcomes, " says Ziyad Al-Aly, a physician-scientist at the Veterans Affairs St. Louis Health Care System in Missouri, who led the work.

“但没有人全面调查过GLP-1受体激动剂所有可能健康结果中的有效性和风险，”密苏里州圣路易斯退伍军人事务医疗系统的医生兼科学家齐亚德·阿莱说，他领导了这项研究。

Another concern is that GLP-1 agonists might be too good at dampening the pleasure and reward pathways, to the point where they would cause disruptions in mood or motivation.

另一个担心是 GLP-1 激动剂可能过擅长抑制愉悦和奖励回路，以致会导致会破坏情绪或动机。

While these techniques are being used, some medications such as melatonin agonists, non-benzodiazepine sedatives, and occasionally benzodiazepines might be prescribed to help with sleep.

使用着这些方法的同时，一些药物例如褪黑素激动剂、肺苯二氮卓类药物镇静剂，或者偶尔遵医嘱使用苯二氮卓类药物，可帮助睡眠。

Semaglutide belongs to a class of drugs known as GLP-1 agonists, which were designed to treat type 2 diabetes.

塞马格鲁肽属一类叫做GLP-1激动剂的药物，该药物旨治疗2型糖尿病。

There are also medications that act on nicotinic receptors like buproprion and partial nicotine receptor agonists like varenicline which help reduce withdrawal symptoms and prevent relapse.

还有一些药物可以作用烟碱受体，如盐酸安他非酮，以及烟碱受体部分激动剂，如瓦伦尼克林等，可以帮助减轻戒断综合征效应，防止复发。

If those results are promising, these experts are hoping that GLP-1 agonist drugs can one day give clinicians and patients another addiction treatment option.

如果这些测试有了结果，专家希望GLP-1促效药有一天能为临床医生和患者提供另一种成瘾治疗选择。

Definitely. There are also a lot of questions about whether or not a GLP-1 agonist would be a lifelong addiction treatment.

绝对的。还有很多关 GLP-1 激动剂是否会是终身脱瘾治疗的问题。

The Food and Drug Administration hasn't approved GLP-1 agonists to be used for addiction.

食品药品监督管理局尚未批准 GLP-1 激动剂用脱瘾。

So we know that GLP-1 agonists have been proven safe for most people, but experts are concerned that they could cause problems in people who are malnourished from opioid or methamphetamine use, for instance.

我们知道 GLP-1 激动剂被证明对大多数人安全，但专家担心会让因阿片或甲基苯丙胺等使用而营养不良的人出问题。

There are reliever medications, which treat symptoms immediately, and contain beta agonists.

存缓解药物，它们能立即治疗症状，并含有β受体激动剂。