That's where Alzheimer's patients have a buildup of toxic proteins called amyloid.

在这个部分，阿尔茨海默病患者积累了一种叫做粉样蛋白的有毒蛋白质。

The drugs target a protein buildup, called beta amyloid, in the brain of Alzheimer's patients.

这些药物针对的是阿尔茨海默病患者大脑中一种被称为β粉样蛋白的蛋白质堆积。

The amyloid cascade hypothesis remains the most influential explanation for how Alzheimer's develops.

粉样蛋白级联假说仍然是阿尔茨海默病如何发展的最具影响力的解释。

So um, I don't know how much time we have to get into detail, but amyloid or beta-amyloid is this protein that the neurons secrete that even healthy people's brains secrete, it's not specific to Alzheimer's.

我不知道我们还有多少时间讲清细节，但是粉样蛋白或者 β-粉样蛋白是大脑神经元分泌的一种蛋白质，人也会分泌这种蛋白，不是只有老年痴呆患者才有。

Saying amyloid is a hallmark, though, is different than saying it's a cause.

然而，说粉样蛋白是这种病的一个特征，与说它是一个病因不同。

Two of the newest look for fragments of these amyloid proteins in your blood.

其中两种最新的检测方法是在血液中寻找粉样蛋白的碎片。

The study used brain scans and samples of spinal fluid to look at the biological hallmarks of Alzheimer's, amyloid plaques and tangles made up of proteins called tau.

这项研究利用脑部扫描和脊髓液样本阿尔茨海默氏症的生物学特征、粉样斑块和由tau蛋白构成的缠结。

Because a common explanation for the disease's symptoms is that they're at least partly caused by plaques in the brain made of the compound amyloid beta.

因为对这种疾病症状的一个常见解释是，它们至少部分是由大脑中类粉β复合物组成的斑块所致。

Now, along with insulin, beta cells also secrete islet amyloid polypeptide, or amylin, so while beta cells are cranking out insulin they also secrete an increased amount of amylin.

同时，除胰岛素外，β细胞也会分泌胰岛粉样多肽（胰素），所以当β细胞分泌更多胰岛素时，它们也分泌了更多的胰素。

Alzheimer's is a fatal, progressive brain disorder, where protein fragments called amyloid plaques build up in the brain, causing cell death and brain damage.

阿尔茨海默病是一种致命的、进行性脑部疾病。大脑中称为粉样斑块的蛋白质碎片会积聚，导致细胞死亡和脑损伤。

They suggest that by the time most patients take them, the illness is too far gone to be stopped by amyloid removal alone.

他们认为，当大多数患者服用它们时，病情已经严重到无法仅通过去除粉样蛋白阻止。

They're both antibodies, and the antibodies are aimed at a nasty protein called amyloid, which builds up in the brain as Alzheimer's disease progresses.

它们都是抗体，抗体针对的是一种叫做粉样蛋白的异体蛋白质，随着阿尔茨海默病的发展，粉样蛋白会在大脑中积累。

For decades, a leading theory stated that the amyloid beta protein formed sticky plaques in the brain that were the main cause of Alzheimer's.

几十年，一个主导理论是，粉样β蛋白在大脑中会形成粘性斑块，这是导致阿尔茨海默症的主要原因。

Protein levels also closely corresponded with the severity of amyloid plaques and tau tangles in brain tissue from people who had died with Alzheimer's.

脑源性 Tau 蛋白质水平还与阿尔茨海默病患者脑组织中的粉样斑块和 Tau 蛋白缠结的严重程度密切相关。

Familial amyloid cardiomyopathy is a genetic disorder where mutant transthyretin protein, or TTR, is misfolded and prone to depositing in the heart tissue.

家族性粉样心肌病是一种基因疾病：突变的转甲状腺素蛋白（TTR）折叠错误，并易于在心脏组织中沉积。

It works by clearing a rogue protein called amyloid, which builds up in sticky clumps in the brains of Alzheimer's patients.

它的工作原理是清除一种名为粉样蛋白的无赖蛋白质，粉样蛋白会在阿尔茨海默氏症患者的大脑中形成粘性团块。

Its usual signs, or " biomarkers, " are amyloid plaques and abnormal tau protein that leads to tangles that damage neurons.

其常见的标志，或“生物标志物”，是粉样斑块和异常的tau蛋白，这会导致缠结，从而损害神经元。

The new technique looks for protein called amyloid beta that associated with the condition. Our health correspondent James Galiga reports.

这项技术是要寻找一个被称为粉状β肽的蛋白质，该物质与阿尔兹海默病有关。以下是我台医疗记者吉姆斯·加里盖的报道。

Higher deposition of amyloid goes hand-in-hand trade loss of function in Alzheimer's disease.

粉样蛋白的高度沉积与阿尔茨海默病患者的功能丧失密切相关。

Patients were also switched to inactive substances if enough amyloid cleared out.

如果清除了足够多的粉样蛋白，患者也会改用非活性物质。