We developed a general computational strategy for creating these protein structures that incorporates full backbone flexibility into rotamer-based sequence optimization.
Several chiral aryl diphosphite ligands derived from pyranoside backbones of glucose and galactose were applied in Rh-catalyzed asymmetric hydroformylation of styrene.
In this paper, the new chelating resin (PSIM) with a polythioether backbone bearing imidazole group is first synthesized by the reaction between polychloromethylthiirane and imidazole.