Metformin hydrochloride is an orally administered biguanide widely used in clinical medicine.

盐酸二甲是泛用于床医学类降糖药。

All five biguanides tested interacted synergistically with atovaquone against Plasmodium falciparum in vitro.All of the other compounds tested were either additive or antagonistic.

【文献摘要】The synergistic potential of a range of biguanides, their triazine metabolites, tetracyclines, and pyrimethamine in combination with atovaquone has been assessed.