Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.

近，有研究表明线粒体乙醛脱氢酶是体内催硝酸甘油生物转的主要途径，线粒体乙醛脱氢酶同时具有脱氢酶和酯酶的催，其酯酶可以通过将硝酸甘油脱硝形成一氧氮，进而血管扩张。