Mismatches between myocardial fatty acid uptake and utilization lead to the accumulation of cardiotoxic lipid species,and cause lipotoxic cardiomyopathy.
游离脂肪酸的摄入和利用的失协调导致中脂质积聚并进而起脂毒性病。
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Later symptoms include needing a wheelchair because of severe weakness, developing respiratory failure because of a weak diaphragm, scoliosis, and developing dilated cardiomyopathy and arrhythmias since the dystrophin protein is also expressed in heart muscle.
后期症状包括,由于严重的肌无力需坐轮椅,由于膈肌无力会发生呼吸衰竭、脊柱侧凸,因为抗肌萎缩蛋白也表达于肌纤维,还会引发扩张型肌病和律失常。