The senescent chondrocytes were distributed in the central zone whereapoptotic morphological characteristics obviously appeared, such as pyknosis, karyorrhexis.
气管软骨中央带多见衰老的软骨,并见明显核固缩、核碎裂凋亡形态学特征。
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In healthy people, chondrocytes maintain a delicate balance between breaking down old cartilage—called catabolic activity, and producing new cartilage—called anabolic activity, through the use of both degradative enzymes and synthetic enzymes.
在健康的机体内,软骨细胞在分解老化的软骨(分解作用)和产生新的软骨(合成作用)之间过分解酶和合成酶来保持精细平衡。
MSCs differentiate into adipocytes, osteocytes, chondrocytes, tenocytes, marrow stromal cells, muscle, and perhaps neuronal cells and are being used in early clinical trials to enhance bone marrow grafting and to suppress graft-versus-host disease in allogeneic bone marrow transplants.
MSCs分化成脂肪细胞,骨细胞,软骨细胞,肌腱细胞,骨髓基质细胞,肌和神经细胞,并用于早期临床试验,以增强骨髓移植和抑制同种异体骨髓移植中的移植物抗宿主病。