At this phase condensed, deeply staining chromatin masses are often seen in the nucleoplasm.
Methods Mucosal cells of human oral cavity were stained with Giemsa or Thionin to show the structure of X chromatin.
Each long strand of DNA combines with histones and nonhistone proteins to make up the substance chromatin.
Micrococcal nuclease treatment indicates that the remodeling of the demembranated sperm chromatin has occurred and the structure of nucleosome is formed during nuclear reconstitution.
The researchers think Dsup acts as a sort of chromatin insulator, shielding DNA from attack by hydroxyl radicals.
It is not established, however, that the endonuclease-induced DNA fragmentation itself causes the chromatin condensation.
The chromatin aggregates peripherally under the nuclear membrane, into well-delimited dense masses of various shapes and sizes.
They found that it binds to chromatin, the compact structure that allows long molecules of DNA to ball up and fit into a tiny cell.
It usually involves several genetic mutations in endometrial cells, including of PTEN, a tumor suppressor gene; PIK3CA, an oncogene; and ARID1A, a gene regulating chromatin structure.
These machines are called chromatin remodelers, and the way they work is that they basically scoot the DNA around these histones and they allow new pieces of DNA to become exposed.
这些“机器”被称为染色质重塑器，它们载着 DNA在组蛋白上移动，让新的 DNA 片段暴露出来。