The researchers think Dsup acts as a sort of chromatin insulator, shielding DNA from attack by hydroxyl radicals.

他们发现，它能与染色质相结合，染色质是种紧密的结构，这种结构能使DNA的长分子聚集起来，并适合小细胞。

It is not established, however, that the endonuclease-induced DNA fragmentation itself causes the chromatin condensation.

细胞体积和形状的改变部分因于凋亡细胞内谷氨酰胺转移酶活性的诱导。

The chromatin aggregates peripherally under the nuclear membrane, into well-delimited dense masses of various shapes and sizes.

细胞核本身可能崩解，产生两或多核碎片。

They found that it binds to chromatin, the compact structure that allows long molecules of DNA to ball up and fit into a tiny cell.

研究人员认为，Dsup作为种染色质绝缘体，可以保护DNA免受羟基自由基的攻击。

It usually involves several genetic mutations in endometrial cells, including of PTEN, a tumor suppressor gene; PIK3CA, an oncogene; and ARID1A, a gene regulating chromatin structure.

它通常涉及子宫内膜细胞的几种基因突变，包括抑癌基因PTEN、原癌基因PIK3CA，及调控染色质结构的基因ARID1A。

These machines are called chromatin remodelers, and the way they work is that they basically scoot the DNA around these histones and they allow new pieces of DNA to become exposed.

这些“机器”被称为染色质重塑器，它们载着 DNA在组蛋白上移动，让新的 DNA 片段暴露出来。