If there were no way out of the pleural space, then it would fill up with fluid, but fortunately, there are lymphatic vessels in the pleura that drain the fluid away and deliver it back into the circulatory system.
Even after it became an accepted treatment for angina, the technical term for chest pain, what exactly nitroglycerine does to the circulatory system remained a mystery for a long time.
And the global circulatory system that delivers 99 percent of international data from point A to points B through C and back again is made of fiber optic cable.
In the same way, your circulatory system starts diverting blood away from the liver because of the high liver pressures, this is known as a portosystemic shunt.
They have been quite aptly defined as: cold-blooded vertebrates with a double circulatory system, breathing through gills, and designed to live in water.