The premature coagulation of the alloy starts to be set.

合金过结开始了。

At this point many of the described symptoms start to develop, like jaundice and pruritus or itchy skin, ascites, hepatic encephalopathy leading to confusion, and easy bruising from low coagulation factors.

肝硬化症状开始出现，如黄疸、皮肤瘙痒、腹水、导致神智不清肝性脑病，以及因因子不足导致瘀斑。

The coagulation cascade starts when one of these proteins gets proteolytically cleaved.

当某一个因子被活化即发生蛋白水解反应时，级联过程就开始了。

Your red blood cells have specialized antigens on them, called agglutinogens, that activate antibodies that work by binding invading cells to each other, which causes coagulation, or the clumping of blood.

你红细胞上有专门抗原，叫做集素原，它激活抗体，通过将入侵细胞相互结合来工作，从而导致，或者结块。

I've had five bypasses of my heart, two years ago. You know, coagulation issues, because COVID causes your blood vessels that react strangely.

两年前，我因为问题做过五次心脏搭桥手术，而新冠会导致心管功能异常。

The coagulation cascade can get started in two ways.

级联反应启动分两种方式。

After that, the coagulation cascade is activated.

之后，级联反应被激活。

Hemophilia usually refers to inherited deficiencies of coagulation factors, which can be either quantitative or qualitative.

友病通常是指遗传性因子缺乏症，可以是数量或者活性上缺陷。

Protein C or S deficiency is suspected in people with a strong family history of coagulation disorders, especially those who suffer from recurrent venous thromboembolisms and experience their first thrombotic event before age fifty.

有明显功能障碍家族史患者可怀疑蛋白C或蛋白S缺乏症，尤其是反复出现静脉栓栓塞，且于50岁之前发生第一次栓塞患者。

This increases circulating factor V and factor VIII levels, and " tips the scale" toward coagulation, putting them at increased risk for thrombosis, or developing blood clots.

这使得循环中V因子和VIII因子数量增多，更容易发生，导致栓形成风险增加。

The main role of protein C and protein S is to prevent excess coagulation, or fibrin formation, during secondary hemostasis.

蛋白C和蛋白S主要作用是在二期止时防止过度（即纤维蛋白形成过多）。

This animal byproduct, produced in the stomachs of certain mammals, can accelerate and control coagulation.

这种动物副产品源自某些哺乳动物胃部，能够加速并调控固过程。

It's because it reduces blood clots, reduces coagulation.

这是因为它减少了栓, 减少了。

So the final war is between this quote-unquote mafia, this coagulation of wealthy, capitalistic government interests against, you know, just people who are trying to live and survive.

所以最终战争是在这个所谓黑手党——即财富和资本主义政府利益结体——与那些仅仅试图生存和生活普通人之间展开。

This means they act like brakes on coagulation, limiting clot formation and preventing clots from growing too big.

它们在过程中起到刹车作用，限制块形成，并防止块生成得太大。

So essentially, there's three processes, there's coagulation, then the next phase is flocculation, and then the last piece is the disinfection.

- 本质上， 整个过程分为三个步骤：首先是混，接着是絮，最后一步则是消毒。

An insufficient concentration or decreased activity of any coagulation factor can cause hemophilia, except factor XII deficiency which is asymptomatic.

任何因子浓度不够或者活性降低都会引起友病，一个例外是缺乏因子XII话，不会有相关症状出现。

A plaque may become inflamed and rupture, exposing substances that promote coagulation, producing a blood clot on top of the plaque.

随着时间推移慢慢积累。斑块可能会发炎破裂，暴露促进物质，在斑块顶部产生块。

Alright, as a quick recap - Hemophilia is a bleeding disorder that is caused by an impaired coagulation cascade.

好！快速回顾一下：友病就是由级联反应受损造成疾病。

Signs and symptoms hemophilia A and B are nearly clinically identical, which makes sense since factors VIIIa and IXa work together in the coagulation cascade to activate factor X.

友病A和B体征和症状在临床上几乎相同，也说得通，因为因子VIIIa和IXa在级联反应中，共同作用以激活因子X。