Histopathology showed moderate hyperkeratosis and rete ridge elongation with the epidermal thinning above the papillar layer and a few melanophages in the dermis.
That proboscis though keeps going into the dermis, since the epidermis just gets oxygen from the air and doesn't have its own blood supply, whereas the dermis does, and this is what our mosquito's after, right, the blood meal.
Then it forms dense irregular tissue, whose fibers are thicker and arranged erratically — it's found wherever tension might be exerted in lots of different directions, like the leathery dermis underlying your skin.
These microbes, which include bacteria and fungi, thrive in the sebum, an oily substance that's secreted onto the skin's surface by sebaceous glands nestled inside the dermis.
Say you're in the room where you're, like, practicing thumb calisthenics — which probably isn't a thing — but the room is a little chilly, so the blood feeding your dermis loses a lot of heat to that cold air.
Made up of three layers, the epidermis, dermis, and hypodermis, skin's thickness varies from 0.5 millimeters at its thinnest and up to four millimeters at its thickest.
As these cells travel through the lymphatic system, some of them are carried back with a belly full of dye into the lymph nodes while others remain in the dermis.
The needles punch through the epidermis, allowing ink to seep deep into the dermis, which is composed of collagen fibers, nerves, glands, blood vessels and more.