A person who always has a stick-in-the-mud attitude could also be called a downer.

一个总墨守成规的人也以被称为扫兴者。

Similar to the party pooper is a Debbie downer.

和“令人扫兴的人”类似的还有“Debbie downer”。

Oh, God. I shouldn't be here. -Come on. Don't be a downer.

啊。我不该来这儿。-拜托，别那么扫兴。

In some situations, using downers can lead to death.

在一些情况下，便用镇导致死亡。

Downers are known to cause headaches, feelings of sadness and a weak pulse.

镇据悉以引起头痛，伤感和脉搏虚弱。

You know, if you're on a downer, if you will, sometimes your body just responds accordingly.

你知道，如果你情绪低落，如果你愿意，有时你的身体会做出相应的反应。

I don't want to be a downer here, but life on Earth has

也许不，但我们快没时间了。

Not to be a downer but it just doesn't seem practical within the limited time frame given by 2050.

不让人沮丧，但在到 2050 年的有限时间内，这似乎并不现实。

Most of epigenetic research has really focused on stress, anxiety, depression -- kind of a downer, kind of bad things.

大多数的表观遗传学研究都集中在压力，焦虑，抑郁上—某种负面情绪，某种不好的事情。

Some of these are like downers and I'm totally willing to admit that, but this is an absolute dance song.

其中有些会让人感到很沮丧，但这首歌绝对一首舞蹈佳曲。

A person who always has a stick-in-the-mud attitude could also be called a downer. This means they bring people down.

一个总墨守成规的人也以被称为" downer" （扫兴的人）。这意味着他们总会让气氛冷场。

And the researchers found that just the act of scheduling an activity actually put kind of a downer on things.

研究人员发现，仅仅安排活动的行为，就能让事情变得有点沮丧。

I'm- I'm making it all about me. What a downer. It's your evening. Let's make it great, man. - No. No.

我把自己弄成主角了。真扫兴。今晚的主角你。让今夜此生难忘吧。-没没。

You don't have to sound a downer alert.

- 你不必听起来像个扫兴的人。

You know, they took a lot of these downers and would sit there.

你知道，他们吃了很多这种镇，然后就坐在那里。

I feel like sometimes I'm a real downer.

我觉得有时候我真个扫兴的人。

There are a lot of downer things, but I'm still a pretty happy person.

尽管生活中有许多令人沮丧的事情，但我依然个相当快乐的人。

Don't let me… he's equally melancholy and despairing, a bit of a downer.

别让我...他同样忧郁和绝望，有点沮丧。

So you get this classic cycle of uppers and downers.

所以你就得到了这种典型的兴奋和镇循环。

What a downer, but I'm going to pick it back up.

真扫兴，不过我会重新振作起来。