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In addition, only certain murine mAb isotypes hae been shown to effectiely bind to and actiate elements of the human immune system, thereby triggering cytotoxic effector functions10.

另外,只有某些亚型的可以有效的结合并激活人免系统,以激发毒作用[10]。

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NK cell will trigger effector functions(cytolysis) by KAR,if target cell loses appropriate ligands recognized by KIR.

如果失去KIR所识别的配体,NK即可通过KAR对进行攻击。

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Crash Course 解剖生理学篇

They extend from the cranium and sacrum where they start, out to the lungs or liver or bladder — wherever their effector is — where they reach their ganglion.

从颅骨和骶骨开始,延伸到肺、肝或膀胱——无论它应器在哪里——它会抵达神经节。

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Osmosis-微生物

However, Legionella has a type IVB secretion system, which uses effector proteins to prevent phagolysosomal fusion.

但是,军团菌有套IVB分泌系统,会利用蛋白阻碍吞噬体和溶酶体融合。

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Crash Course 解剖生理学篇

Those postganglionic neurons then carry the action potential to the effector organs — in this case, let's say your leg muscles, which are going to need an influx of blood if they're going to hustle you out of that house.

节后神经元然后将动作电位传递到器官——在这种情况下,比方说你腿部肌肉,如果它把你赶出房子,它大量血液。

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Crash Course 解剖生理学篇

But they do have a lot of distance to cover, on the other side of the ganglion, in order to reach their effectors. So naturally the fibers leading out of the ganglia are a lot longer.

但是它确实有很长距离,在神经节边,为了到达它应器。所以自然地,从神经节延伸出来纤维长得多。

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Crash Course 解剖生理学篇

Since parasympathetic ganglia are so close to, or even inside of, their effector organs, the preganglionic fibers are a lot longer.

由于副交感神经节如此接近其器官甚至在它内部,节前纤维长得多。

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Crash Course 解剖生理学篇

Well, it all depends on the particular kind of receptors that an effector has for receiving that chemical.

嗯,这完全取决于应器接收这种化学物质特定受体。

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Crash Course 解剖生理学篇

For now you learned that your sympathetic nervous system controls your body's stress response and how the signals in your sympathetic nervous system travel to an effector, using the neurotransmitters acetylcholine in the ganglion and norepinephrine at the effector.

现在你知道了你交感神经系统控制你身体压力反应,以及交感神经系统中信号如何传递到应物,使用神经节中神经递质乙酰胆碱和应物处去甲肾上腺素。

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Crash Course 解剖生理学篇

And that one, in turn, leads to an effector organ, where it synapses again to create whatever response was signaled — like sending more blood to your skeletal muscles, or making your heart pump faster.

这根神经纤维又导致器官,在那里它再次突触以产生所发出任何反应——比如向骨骼肌输送更多血液,或者让你心脏泵速加快。

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Paper Talk

They found cells with hybrid phenotypes overlapping significantly with traditional resident memory T cells, T-M-E-M, and effector T cells, T-E-F-F.

发现了具有混合表型细胞,这些表型与传统驻留记忆T细胞(T-M-E-M)和T细胞(T-E-F-F)显着重叠。

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Crash Course 解剖生理学篇

And an effector is just any structure that receives and reacts to a motor neuron's signal, like a muscle contracting or a gland secreting a hormone.

应器只是任何接收运动神经元信号并做出反应结构,就像肌肉收缩或腺体分泌激素样。

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呼吸系统

Finally, the integration center sends signals to effectors, which then act to restore homeostatic balance.

最后,整合中心向应器发送信号,然后应器采取行动恢复体内平衡。

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Paper Talk

When they looked closely at the lymphoid cells, so the T cells and NK cells, the natural killer cells, they found notably lower effector states.

当他仔细观察淋巴细胞,即T细胞和自然杀伤细胞(NK细胞)时,发现其状态明显降低。

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2017级专外有声

Efferent neurons transmit signals from the CNS to the effector cells and are sometimes called motor neurons.

传出神经元将来自CNS信号传递到细胞,有时为运动神经元。

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Crash Course 解剖生理学篇

It's up to those neurotransmitters and hormones, and the receptors on the corresponding effectors, to make sure that everyone is on the same page.

这取决于那些神经递质和激素,以及相应应器受体,确保大家都保持着统步调。

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Paper Talk

And third, even if some immune response starts to get organized, the TME hypoxia steps in to shut it down by crippling the function of the tertiary lymphoid structures, favoring suppressive tregs over effector T cells.

第三,即使某些免疫反应开始组织起来,肿瘤微环境缺氧状态也会通过破坏三级淋巴结构功能来将其扼杀,从而有利于调节性T细胞而非T细胞。

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Crash Course 解剖生理学篇

The sympathetic nervous system is set up in such a way that even a small stress signal sent down one path could trigger a response in many effectors at once.

交感神经系统是这样建立,即使是沿着条路径发出微小压力信号也能同时触发许多应器反应。

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Crash Course 解剖生理学篇

Once the integration center interprets the signal, it transmits the message to motor neurons, which send an action potential back down your leg, where it reaches an effector.

旦整合中心解释了信号,它就会将信息传输到运动神经元,运动神经元将动作电位发送回你腿,到达应器

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Paper Talk

Shifting focus from the adaptive T-cell targets to these innate effectors seems key.

将关注点从适应性T细胞靶点转向这些先天细胞似乎至关重

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Crash Course 解剖生理学篇

In the case of norepinephrine, its effector is smooth muscle — the muscle that controls all of your involuntary functions of hollow organs, like the stomach, and bladder, and also your blood vessels.

就去甲肾上腺素而言,它应器是平滑肌——控制所有中空器官无意识功能肌肉,比如胃、膀胱,还有你血管。

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Paper Talk

But key effector molecules, the things T cells use to kill target cells, like granzyme B, GZMB, and perforin, were significantly enriched in these HMW aggregates.

然而,关键分子——T细胞用于杀伤靶细胞物质,如粒酶B(GZMB)和穿孔素,在这些高分子量聚集体中显着富集。

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