In addition, only certain murine mAb isotypes hae been shown to effectiely bind to and actiate elements of the human immune system, thereby triggering cytotoxic effector functions10.
Once the integration center interprets the signal, it transmits the message to motor neurons, which send an action potential back down your leg, where it reaches an effector.
Their ganglia, for example, are located in different places: The sympathetic ganglia are located near the spinal cord, while on the parasympathetic side, they're close to the effectors.
But key effector molecules, the things T cells use to kill target cells, like granzyme B, GZMB, and perforin, were significantly enriched in these HMW aggregates.