Human defensins,found in the blood,intestinal tract and epithelial cells,are small,cystin-rich cationic peptides with special structure.
人类防御素是一种存在于血液、
道及表皮细胞中具有特殊空间结
,富
精氨酸
阳离子多肽。
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Initially these inflammatory changes are completely reversible, but over the years irreversible changes start to take place —edema, scarring, and fibrosis build up, leading to thickening of the epithelial basement membrane, which permanently reduces the airway diameter.
最初这些炎症变化是完全可逆
,但是随时间进展,不可逆
变化开始发生,出现水肿、瘢痕、纤维化等症状,导致上
基底膜增厚,从而永久性地减小气道直径。