E2 protein, including hypervariable region 1 (HVR1) in the N-terminal region, contains some epitopes that can induce neutralizing antibodies.

包括高变区的E2有中性抗原表位，能诱导机体产生中性抗体。

After the tolerizing regimen, the host is withdrawn from the suppressive agents, but is able to maintain specific immune tolerance to the immunogenic epitopes present on the toleragen.

在致耐受方案后，将免疫抑制剂撤离，仍能保持对存在于耐受原上的免疫原性表位的特异性免疫耐受。