The effect this has on excitability of myocytes, however, is complex.

然而，这对心肌影响是复杂。

While initial changes seem to increase myocyte excitability; further rise of potassium has the OPPOSITE effect.

初始变化可能增加心肌，钾进一步升高却具有相反作用。

The result is a reduced excitability or responsiveness of the neurons and muscles in the heart.

这导致心脏神经元和肌肉或反应降低。

This reduces the heart's excitability and suppresses reentrant tachycardia.

这降低心脏和抑制折返快速心律失常。

Now, as you may know, the binding of glutamate to the NMDA receptor results in an influx of extracellular calcium, which controls membrane excitability and synaptic transmission.

现在，如你所知，谷氨酸与NMDA受体结合导致内流外钙，控制膜和突触传递。