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So in fibrotic livers you can find cannabinoid receptors that have both anti- and pro-fibrogenic effects.

因此在发生纤维化体既有抗纤维化作用也有促纤维化作用。

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How do these bands of fibrotic tissue form though?

那么这些如何形成的呢?

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As this fibrotic tissue builds up, it starts to compress the central veins and sinusoids.

堆积在一起的组织会挤压中央静脉和血窦。

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Osmosis-消

Most commonly, this happens because of hepatic cirrhosis, which is when the liver tissue is replaced by fibrotic functionless tissue.

它大多数由肝引起,即肝脏组织被无功能的组织替代。

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Osmosis-解剖与生理

If fertilization doesn't happen, then the corpus luteum stops making hormones after around 10 days, becomes fibrotic, and is called the corpus albicans.

如果次级卵母细胞没有受精,大概10天之后,黄体就会停释放激素而,形成白体。

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Osmosis-生殖

If fertilization doesn't happen, then the corpus luteum stops making hormones after approximately 10 days, becomes fibrotic, and is called the corpus albicans.

如果未受精,黄体会在大概10天后停生成激素,并变成白体。

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Osmosis-消

Also with cirrhotic liver tissue, you'll see that in between these clumps of cells or nodules, is fibrotic tissue and collagen.

的肝脏组织里,成堆的细胞或结节之间,还有组织和胶原的存在。

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Osmosis-消

Alright, as a quick recap, cirrhosis is when inflammation and liver damage causes the liver to become fibrotic and develop scar tissue.

得!快速总结一下:肝指由炎症和肝脏损伤导致肝脏,并形成瘢痕组织。

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Osmosis-消

As part of the subsequent healing process pancreatic stellate cells lay down fibrotic tissue which causes narrowing, or stenosis of the ducts, as well as acinar cell atrophy.

作为后续修复愈合过程的一部分,胰腺星状细胞会产生组织,造成导管狭窄及腺泡细胞萎缩。

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Osmosis-消

If we zoom out a bit and look at it with the naked eye, we'll again see these nodules, which have fibrotic protein bands in between.

如果我们直接通过肉眼直接观察肝脏,我们仍会看到这些结节以及填充在他们之间的蛋白质

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Osmosis-消

The fibrotic tissue, pressure buildup, and diversion of blood from the hepatic circulation essentially reduces the number of functional sinusoidal veins, and the number of functional portal triads in general.

组织形成、门静脉高压和肝循环血液分流,最终导致了可用的血窦静脉数量的减少,以及整体上可用的门脉三联管数量减少。

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Osmosis-肌骨

In the short term, there is muscle regeneration resulting in muscle fibers of different sizes, but in the long term, the muscles atrophy and are infiltrated by fat and fibrotic tissue, which leaves them really weak.

短期内,肌肉再生造成大小参差的肌细胞,但长期下去,肌肉萎缩并且脂肪组织和结缔组织增生渗入其间,导致肌肉无力。

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