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Hematologic studies revealed severe hyperphosphatemia, hypocalcemia and metabolic acidosis.

血液学研究显示有磷血症、低钙血症和代谢性酸毒。

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Tetany, epilepsy, neuro-psychiatrical symptoms, hypocalcemia, hyperphosphatemia were common clinical manifestation.There was also low level of PTH, except pseudohypoparathyroidism.

临床表现为手足抽搐、癫痫神症状、血钙降低、血磷升、除假性甲旁减外血PTH均降低。

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With all that in mind, hyperphosphatemia can develop a few different ways.

综上所述,高磷过几种不同的方式发展。

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Osmosis-泌尿

Mild hyperphosphatemia doesn't usually cause symptoms, but severe hyperphosphatemia can make neurons more excitable.

轻度高磷常不会引起症状,但重度高磷症会使神经元更容易兴奋。

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Osmosis-泌尿

With long-term hyperphosphatemia, the whole kidney can eventually turn into bone, which is called nephrocalcinosis.

长期患有高磷症,整个肾脏最终能会变成骨头,这叫做肾钙化病。

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Osmosis-泌尿

Any time a lot of cells die, that phosphate gets spilled into the bloodstream, causing hyperphosphatemia.

每当大量细胞死亡时,磷酸盐就会溢出中,导致高磷症。

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Osmosis-泌尿

A final cause of hyperphosphatemia relates to the fact that most phosphate in the body is within the cells.

高磷症的最后一个原因,与体内大多数磷酸盐在细胞内有关。

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Osmosis-泌尿

All right, so since, again, parathyroid hormone causes excretion of phosphate and reabsorption of calcium, then another cause of hyperphosphatemia is hypoparathyroidism, when the parathyroid glands don't produce enough parathyroid hormone in the first place.

因为甲状旁腺激素会导致磷酸盐的排泄及钙的再吸收,那引发高磷症的另一原因就是甲状旁腺功能减退,也就是当甲状旁腺首先不能产生足够的甲状旁腺激素时。

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