The immunohistochemical studies demonstrated that the majority of tumor cells were immunoreactive for neuroendocrine markers that included chromogranin A, synaptophysin and neuronspecific enolase.
Methods The expression of FHIT and PCNA protein in 10 normal endometria, 16 endometrial atypical hyperplasia and 44 endometrial carcinoma tissues was observed by immunohistochemical S-P method.
Diagnosis is made with biopsy of lesions and microscopic examination which can detect spindle cells and also with immunohistochemical staining which detect the presence of LANA-1.