The classical ones are things like chronic congestive heart failure, chronic pulmonary disease, diabetes and anybody who really is on any immunosuppressive regimen.
But in most of the body, they get eliminated by the immune system—except in the core of the tumor because the tumor is an immunosuppressive environment.”
To reduce severity of flares, corticosteroids may be used to help limit the immune response, and finally, if symptoms are really severe, certain immunosuppressive drugs might be used.
However, people who are immunocompromised, such as people with AIDS, people who have undergone an organ transplant or people who take immunosuppressive medications, are at risk for developing the disease.