P-Brom-ethylphene was prepared by brom-phene by means of Friedel-Crafts and Huang Ming-long reactions. The synthesis can be industrialized because of good quality, high yield and low cost.
Since typhoid fever is one of those olde-timey diseases that isn't talked about much in the modern, industrialized world, this conversation deserves a short foreword on what exactly the disease is.
In modern industrialized nations, thanks to a combination of less physical activity and diets that are loaded with calories and sugar and salt and fat, increased weight alone puts humans at risk of at least 13 types of cancer.
A collapse of the industrialized world literally means that the majority of people alive today would perish since without industrial agriculture we would no longer be able to feed them.
American life on the eve of the Civil War, in the north, in the south and in the rapidly growing Midwest. By roughly 1850 the industrialized north and agricultural south were on two different economic paths.