Take the experimental rats into 8 groups including 3 groups for therapeutic dose,3 groups for toxic dose and 2 groups for lethiferous dose, with 10 rats for each group and male and female for half.

将实验小鼠（幼年）分8，治疗3，毒3，致死2，每10只，雌雄各半。

Method Hepatic and renal functions,and tissue biopsy were measured in rats with therapeutic,toxic and lethiferous dose treatment after a period of time.

分别测定治疗、毒、致死小鼠在用药一段时间后的肝肾功能,并进行织病理学检查。