The consequence is to inactivate the gene being methylated.

甲基化作用将使甲基化的基因失去活性。

As we age, some stretches of DNA get more methylated, and others less.

随着年龄的增长，一些DNA片段的甲基化程度会上升，而另一些则会下降。

Newborns whose mothers suffered from depression while they were pregnant are known to have more highly methylated glucocorticoid-receptor genes than others.

新生儿的母亲若是在怀孕期间现抑郁症状，他们糖皮质激素受体基因的甲基化程度就会比其他新生儿更高。

Translocations can disrupt SNRNP and move the small nucleolar RNA genes away from their imprinting center, causing them to get methylated and turned off.

SNRNP基因易位会破坏小核内核糖核蛋白（SNRPN），并将核仁小RNA基因记中心，导致这些基因的甲基化沉默。

In one famous experiment, when mother rats weren't attentive enough to their pups, genes in the babies that helped them manage stress were methylated and turned off.

在一个着名的实验中，当母老鼠对它们的幼崽不够关心的情况下，幼崽体内帮助它们管理压力的基因甲基化并且隐藏了。

If the paternal imprinting center is mutated, the region gets methylated and those genes get turned off, meaning that both the maternal and paternal genes are silenced.

如果父源记中心突变，基因将被甲基化沉默，导致母源和父源基因都处于沉默状态。

If both copies of chromosome 15 were derived from the mother, that means all the prader willi genes are methylated and silenced, since there's no unsilenced paternal genes.

如果15号染色体的两条同源染色体都来自母方，就意味着所有的普拉德-威利基因都被甲基化沉默，根本就没有父源基因的表达。