These three are all technically monoamines but norepinephrine and dopamine are classified as catecholamines.

严格说来，三种激素都属于，但去甲肾上腺素和多巴也被归为儿茶酚。

I'm leading a study to see if deficiency of the monoamine oxidase enzyme leads to paralyzing fear in monkeys.

我将带领团队研究氧化酶缺失是否会导致猴子精神崩溃。

You know, not a lot of people know this, but the monoamine oxidase enzyme was discovered by a woman, Mary Bernheim.

很多人都不知道氧化酶是由一位名叫玛丽·伯恩海姆女性发现。

Both drugs affected a class of neurotransmitters called monoamines.

两种药物都会影响一类称为神经递质。

Two of the older classes are called the monoamine oxidase inhibitors and the tricyclic antidepressants.

其中两较早类别称为氧化酶抑制剂和三环类抗抑郁药。

The monoamine neurotransmitters, serotonin norepinephrine and dopamine in the brain.

大脑中神经递质，包括血清素、去甲肾上腺素和多巴。

NNDMT, and then also the prevalence of syrian rue, which contains monoamine oxidase inhibitors.

NNDMT，以及含有氧化酶抑制剂叙利亚芸香普遍存在。

In general, I think it's underrated for its Notropic or basically monoamine oxidase inhibition.

总来说，我认为它在作为聪明药或基本上作为氧化酶抑制剂方面被低估了。

It almost seems like how we're talking about the monoamine hypothesis hasn't changed much.

我们谈论假说方式几乎好像没什么变化。

These two so-called " antidepressants" blocked the usual depletion of the catecholamines dopamine and norepinephrine and blocked the depletion of the monoamine serotonin.

两种所谓“抗抑郁药”阻止了儿茶酚、多巴和去甲肾上腺素消耗，也阻止了 5-羟色种消耗。

Very similarly, there are medications like selegiline which inhibits monoamine oxidase B, also known as MAO-B, which is another enzyme that metabolizes dopamine.

类似地，像司来吉兰等药物可以抑制氧化酶B，即MAO-B，另一种可以分解代谢多巴酶。

After the discovery that apronized acted as an antidepressant, it was shown to be a monoamine oxidase inhibitor, an MAOI.

在发现异烟肼具有抗抑郁作用后，人们发现它是一种氧化酶抑制剂，即MAOI。

Monoamines are neurotransmitters, chemical messengers that play a key role in how signals are transmitted across connections, synapses in the brain.

类是神经递质，即在大脑中连接处——突触传递信号时起关键作用化学信使。

And ketamine may affect these connections, not by altering monoamines, but with an entirely different neurotransmitter, glutamate.

而氯酮可能通过一种完全不同神经递质谷氨酸，影响些神经连接，而不是通过改变类物质。

Time ticked on, and more and more antidepressants became available, still focused on increasing the levels of monoamines in the brain.

时间流逝，越来越多抗抑郁药物问世，仍然集中在提高大脑中类物质水平上。

Ipronaizid, imipramine, and other drugs like them were thought to restore that balance by increasing the availability of monoamines in the brain.

异丙肼、丙咪嗪和其他类似药物被认为可以通过增加大脑中可用性来恢复种平衡。

And if SSRIs didn't work, other drugs that aim to raise levels of a different combination of monoamines could be tried out.

如果SSRIs无效，还可以尝试其他旨在提高不同组合水平药物。

In the 1970s, several different researchers converged on an answer: the most effective antidepressants all seemed to act on one monoamine called serotonin.

在 20 世纪 70 年代，几位不同研究人员得出了一答案：最有效抗抑郁药似乎都作用于一种叫做血清素。

Most antidepressants to date have been based on the monoamine hypothesis, which holds that depression is caused by low levels of a class of chemical messengers.

迄今为止，大多数抗抑郁药物都是基于假说，该假说认为抑郁症是由一类化学信使水平低下引起。

The discovery of these antidepressant drugs gave rise to the chemical imbalance theory, the idea that depression is caused by having insufficient monoamines in the brain's synapses.

些抗抑郁药物发现引发了化学失衡理论，认为抑郁症是由于大脑突触中不足引起。