Some become myeloid progenitor cells whereas others become lymphoid progenitor cells.

一些会成为髓系祖，其它的会成为淋巴系祖。

Even in people with acute myeloid leukemia— an aggressive blood cancer — chemotherapy puts an estimated 60% of patients under 60 into remission following their first phase of treatment.

即使在患有急性髓性白血病（侵袭性血液癌）的人中，60％的年龄在60岁以下的患者接收他们的第一阶段化疗后症状缓解。

Lonely people have unusually low numbers of a type of myeloid cell that generates what are known as interferon responses, which hamper viral replication.

孤独的人他们血液中骨髓的数量异常的低，骨髓可以产生干扰素反应，阻碍病毒复制。

Participants had their blood drawn in order to examine their myeloid responses.

参与者抽血检查他们的骨髓反应。

That, of course, promotes further feelings of loneliness. Which, in turn, trigger a further myeloid response. And so on.

当然，进一步加剧了孤独感，反过来会进一步触发骨髓反应。等等。

Instead of looking only at participants' myeloid responses, she also asked them specific questions about loneliness.

不仅观察了参与者的骨髓反应，还询问了一些关于孤独的具体问题。

These correlations are intriguing, but do not explain which comes first, the loneliness or the myeloid response.

些相关性很有趣，但并不能解释孤独和骨髓反应哪个更重要。

And then she said it's acute myeloid leukemia.

然后是急性粒白血病。

First, the myeloid text high group.

首先，髓系高表达组。

This one is dominated by myeloid cells, those macrophages we discussed.

一类主要由髓系构成，也就是我们之前讨论过的巨噬。

Well, they analyzed the nearest neighbor interactions across 17 different tissue sections, and there were clear patterns, sort of rules of engagement, T cells and myeloid cells.

他们分析了17个不同组织切片中的最近邻相互作用，发现了一些清晰的模式，类似于T和髓系之间的“互动规则”。

ANet was also used to identify archetypes within the tumor microenvironment, the MEATs, things like stromal cells, myeloid cells, neutrophils.

ANet还被用于识别肿瘤微环境中的原型，即MEATs，包括成纤维、髓系、中性粒等。

These patients had a lot more non-T cell stuff, specifically myeloid cells, you know, the immune system's first responders, but they can also be really suppressive in cancer settings.

些患者体内有更多非T成分，特别是髓系——免疫系统的第一道防线，但在癌症环境中它们也可能具有很强的抑制作用。

They started with the more common myeloid cells, monocytes, macrophages, neutrophils.

他们首先研究了较为常见的髓系，包括单核、巨噬和中性粒。

But the TME gets dominated by immunosuppressive cell types, particularly myeloid cells and stromal cells.

但肿瘤微环境（TME）被免疫抑制性类型主导，尤其是髓系和基质。

It's biologically known to be a key driver of that RR state, and Scriabin showed these IFNG-producing T cells were signaling to myeloid cells, triggering them to produce the actual pro-inflammatory cytokines like IL-1B, TNF, CCL3.

众所周知，在生物学上是驱动该RR状态的关键因素，Scriabin显示，产生IFNG的T正在向髓系发送信号，从触发它们产生实际的促炎因子，如IL-1B、TNF和CCL3。

T-cells, B-cells, myeloid cells all working together, triggered by the tumor's aggression.

T、B和骨髓共同协作，由肿瘤的侵袭性触发。

Myeloid cells, especially those with CD16, were much better at gobbling up tumor cells when the patient's serum, full of those IgG antibodies, was present.

髓系，尤其是带有CD16的，在患者血清（富含IgG抗体）存在时，吞噬肿瘤的能力显着增强。

Exhausted but ICB-ready T cells, lots of TLSs built with B cells making tumor-specific antibodies, and myeloid cells cleaning up via ADCC.

耗竭但适合免疫检查点阻断治疗的T，大量由B构建的三级淋巴结构（TLSs）产生肿瘤特异性抗体，以及髓系通过ADCC清除癌。