Objective To observe the effects of the fracture healing stimulin, a fracture healing increasing drug from staphylococcus aurous on osteoblasts in vitro .
They're like the construction foremen of your bones, passing along commands to your skeleton's two main workhorses: the osteoblasts and the osteoclasts.
When osteoblasts come in, they secrete a glue-like cocktail of collagen, as well as enzymes that absorb calcium, phosphate, and other minerals from the blood.
Now, even though parathyroid hormone stimulates bone resorption, it's been found that intermittent injections with teriparatide activates osteoblasts more than osteoclasts, therefore increasing bone formation.
So while your osteoblasts are the bone-makers, your osteoclasts are the bone-breakers — which is a kind of violent image. Maybe think of them as like a bone-breaker-downer.
Ok, now, when osteoclasts break down bone faster than the osteoblasts can rebuild it, it results in the lowering of the bone mass and eventually in osteoporosis.