Difloxacin is the fluorinated quinolone approved for use in veterinary only. compared to ciprofloxacin,it provided with better pharmacokinetical and pharmacodynamical feature.

二氟沙星属于兽医专，并且有优于环丙沙星的动学特征，有良好的应前景。

Finally, we gained four esterifiable quinolone analogues (compounds 22 to 25) by modifying the structures of compound 3, 14 and 16 on 3 position.

同时利所成的3，14，16为模板，对它们的3位羧基进行了酯反应成了4个喹诺酮酯类：22—25。