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Hepatic stellate cells (HSteC) are intralobular connective tissue cells presenting myofibroblast-like or lipocyte phenotypes.

细胞是小叶内结缔组织细胞,呈现肌纤维细胞样或脂肪细胞态。

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The shapes of neuronal cell bodies are spherical, ovoid , pyramial, fusiform, stellate or crescentic.

神经元细胞状有圆,卵圆,锥,梭或半月

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Osmosis-消化

So the perisinusoidal space, which literally means " around the sinusoidal space" , and stellate cells are about here.

隙指就是血窦区域;星形就存在于这个空

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Osmosis-消化

When the hepatocytes are injured though, they secrete paracrine factors that " activates" and changes the stellate cells.

然而,当肝细受损时,肝细分泌“旁分泌因子”,可激活并改变星形

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Osmosis-消化

Well fibrosis is a process mediated by special cells called stellate cells, that sit between the sinusoid and hepatocyte, known as the perisinusoidal space.

纤维化过程是由星形调控星形位于血窦和肝细,即窦隙。

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Osmosis-消化

As part of the subsequent healing process pancreatic stellate cells lay down fibrotic tissue which causes narrowing, or stenosis of the ducts, as well as acinar cell atrophy.

作为后续修复愈合过程一部分,胰腺星状会产生纤维化组织,造成导管狭窄及腺泡细萎缩。

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Osmosis-消化

When activated, the stellate cells lose vitamin A, proliferate, and start secreting secreting transforming growth factor beta1, or TGF-beta, which then causes them to produce collagen, which is the main ingredient in extracellular matrix, fibrosis, and scar tissue.

激活后星形失去维生素A,并且开始大量增生,分泌转化生长因子ß,即TGF-ß,随导致其生成胶原;胶原是细外基质、纤维化和疤痕组织重要成分。

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