In mice, widespread deletion of the tumor suppressor Phosphatase and tensin homolog (PTEN) generates hamartomatous intestinal polyps with epithelial and stromal inolement.
在小鼠,广泛肿瘤抑制因子磷酸酶和张蛋白同源物〔PTEN〕产生错构小,含有上皮和间质。
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MSCs differentiate into adipocytes, osteocytes, chondrocytes, tenocytes, marrow stromal cells, muscle, and perhaps neuronal cells and are being used in early clinical trials to enhance bone marrow grafting and to suppress graft-versus-host disease in allogeneic bone marrow transplants.
MSCs分化成脂肪细,骨细,软骨细,肌腱细,骨髓基质细,肌肉和神经细,于早期临床试验,以增强骨髓移植和抑制同种异体骨髓移植中的移植物抗宿主病。