Hyperplasia of synovium leads to formation of pannus which destroys cartilage and bone in the affected joint.
大量增滑膜组织会导,进而逐渐侵蚀软骨,造关节损伤。
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As " type A" cells in the synovium attempt to remove the debris, immune cells like lymphocytes and macrophages are recruited into the synovial membrane, which produces proinflammatory cytokines that ultimately cause inflammation of the synovium as well, called synovitis.
滑膜上的A型细胞努力清除这些碎片的同时,免疫细胞(如淋巴细胞、巨噬细胞)也被募集进入滑膜,产生炎症因子,最终导致滑膜炎。
The synovium's composed of loose connective tissue, blood vessels, lymphatic vessels, and on the surface—" Type A" cells that clear cellular debris and " Type B" cells that produce components of synovial fluid, which helps lubricate the two articular surfaces.
滑膜由松散结缔组织、血管、淋巴管组;滑膜表,A型细胞清理细胞碎屑,B型细胞产生滑液分,滑液能够润滑两块节的表。